Lupine Publishers Current Trends in Gastroenterology and Hepatology

  Abstract The identification of the calcium ration by self-questionnaires validated in the region of Blida and the Wilayas of approximately is one of the rare studies in Algeria. She was interested in a part of the Algerian population with characteristics that do not seem very different from the general population; however, this dietary survey must be supplemented by a study on a representative sample of the general population. The study showed insufficient calcium intake mainly secondary to low consumption of milk and dairy products. This low calcium intake was objectified by the two questioning methods (Fardellone and CERIN), however, it will be desirable to establish Algerian self-questionnaires validated and verified by our learned society. The results obtained are worrying, which obliges us to immediately introduce a prevention and control strategy against the multiple pathologies linked to this low calcium intake, the main one being osteoporosis with its seri...

  Abstract Background : Metabolic bone disorders are frequent in patients with cirrhosis. These two conditions are usually misdiagnosed in Sub-Saharan Africa before the onset of complications. A full evaluation of metabolic bone disorders in patients with liver cirrhosis is difficult in our milieu and osteodensitometry is rarely available. In this preliminary study, we sought to determine the necessity of a cost-effective method, the Nordin’s Index, in the evaluation of osteoporosis in patients with liver cirrhosis. Methods : This was a prospective cross-sectional study from January to May 2017 in Yaoundé. We compared the data of 19 patients (15 men, 4 women) with post viral liver cirrhosis and 17 controls (13 men, 4 women) paired with age, gender and body mass index (BMI). Data collected included vitamin D levels, serum and urine concentrations of calcium and phosphorus, Nordin’s Index and results of the bone mineral density using an x-ray absorptiometry sc...

  Abstract Nonalcoholic fatty liver disease (NAFLD) is described as exposition of multiplex liver metabolic disturbance interconnected with obesity. NAFLD is depicted by steatosis, excessive accumulation of fats in liver, due to triglycerides export and oxidation of fatty acid from plasma and de novo synthesis. Hepatic steatosis can therefore be explained as biochemical outcome of inconsistency between interfused mechanisms of lipid biotransformation. This condition is allied to a range of various modifications in lipoproteins, fatty acids, and glucose metabolisms in organism. So, above metabolic disfunctions are suspected to be the origin of possibility for adverse cardiometabolic risk agents related to NAFLD, like dyslipidemia, Type 2 diabetes mellitus (T2DM), and insulin resistance. Reactive oxygen species (ROS) generation participates as known inducer of inflammation and oxidative stress, that exacerbate this disease. These disorders are hallmarks that worsen ...

Lupine Publishers | Current Trends in Gastroenterology and Hepatology Abstract Over the past several decades, great progress has been made on understanding mechanisms of gastric acid secretion for developing new anti-acid drugs. Until now most commonly used anti-acid drugs are histamine-2 receptor antagonists and proton pump inhibitors (PPIs) for patients to control acid related disease. However, several clinical limitations of these drugs had been reported. Recently, a new generation of potassium-competitive acid blockers (P-CABs) were launched for clinical use. It has been shown that these new drugs are more convenient and powerful to treat gastric acid-related diseases. In this article, we briefly reviewed the clinical use of this new anti-acid drug P-CAB. Keywords: Potassium-competitive Acid Blocker; Potassium channel; H+/K+-ATPase Introduction H+/K+-ATPase (or proton pump), which is expressed in gastric parietal cells, is one of the...

Lupine Publishers |Current Trends in Gastroenterology and Hepatology Abstract Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and is one of the major causes of cancerrelated deaths. HCC is reported to be the second most fatal malignancy. The major risk factors for HCC are well known; the known risk factors include hepatitis C virus (HCV) and hepatitis B virus (HBV). Major advances have been reported in the treatment of HCC. Success of early diagnosis increases when these risk factors are identified, and the cases are followed up. It is reported that in the treatment of early-diagnosed HCC cases, ethanol injection or radiofrequency ablation methods as well as surgical resection should be preferred, particularly in cases without liver cirrhosis and in cases where the tumor is restricted. Similarly, liver transplantation may be an option for patients that meet specific criteria. Keywords: Hepatocellular Carcinoma; Liver Carcinoma; ...

Risk Predictive Factors to Convert Laparoscopic Cholecystectomy into Other Procedures by Eldo E Frezza in Lupine Publishers Abstract Laparoscopic cholecystectomy (LC) is nowadays the procedure of choice for cholecystitis. The intraoperative finding can make this procedure quite tricky such as dense adhesions at calot’s triangle, fibrotic and contracted gallbladder, acutely inflamed or gangrenous gallbladder, cholcystoenteric fistula, etc. There are also risk factors which make laparoscopic surgery difficult like old age, male sex, obesity, previous abdominal surgery, thickened gallbladder wall, distended gallbladder, pericholecystic fluid collection, impacted stone, etc. Methods: This is a one cohort retrospective review of patients admitted to the hospital with acute cholecystitis who during LC were converted to intraoperative cholecystostomy tube placement (CCT) or to open cholecystectomy (OC). Preoperative risk factors to predict difficult cholecystectomy w...

Description of Plasma Concentrations of Free Amino Acidswith Some Clinical Symptoms of Patients Under 5 withShort Bowel Syndrome by Luu Thi My Thuc in Current Trends in Gastroenterology and Hepatology in Lupine Publishers. Amino acid (AA) is the main component of proteins. Changes in levels of plasma AA concentration have been mentioned in some cases such as plasma AA concentrations in chronic kidney disease (CKD) patients are low when inflammation status increases [1] or patients with short bowel syndrome (SBS) undergoing total parenteral nutrition (TPN) have decreasing concentrations of essential amino acids (EAA), increasing rate of malnutrition and complications while for those undergoing part of parenteral nutrition (PN), there was just a decrease in concentrations of two branched chain amino acids, leucin, valine, cysteine, and tyrosine [2]. Autistic children had significant lower plasma levels of leucine, isoleucine, phenylalanine, methionine, cysteine, serine, ty...

Mesenteric Venous Ischemia Secondary to Thrombophilia: Case Report by Amer N in Current Trends in Gastroenterology and Hepatology in Lupine Publishers Mesenteric ischaemia is an uncommon condition with high mortality and morbidity, the causes can be embolic, thrombotic arterial or venous. Mesenteric venous thrombosis is an uncommon cause of bowel infarction, and it accounts for only 2-10% of the cases of Mesenteric Bowel ischaemia. We are reporting an interesting and uncommon case a fifty-year-old Filipina lady, not known to have any previous medical problems, presented to us with severe abdominal pain with minimal signs. Her CT scan confirmed Mesenteric Venous ischaemia and Bowel infarction. The lady was found to suffer from Protein C and S deficiency. https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/mesenteric-venous-ischemia-secondary-to-thrombophilia-case-report.ID.000119.php    https://lupinepublishers.com/ga...

Doggy Style Sex Distorts the Appearance of Face by Rahul Hajare in Current Trends in Gastroenterology and Hepatology in Lupine publishers We report many people using doggy style sex invisible lightening of dark under-eye areas, a tightening and lifting effect, harder more brighter-looking skin around their eyes, and older, weaker, penile fracture first time in India. https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/doggy-style-sex-distorts-the-appearance-of-face.ID.000117.php https://lupinepublishers.com/gastroenterology-hepatology-journal/pdf/CTGH.MS.ID.000117.pdf https://lupinepublishers.com/gastroenterology-hepatology-journal/abstracts/doggy-style-sex-distorts-the-appearance-of-face.ID.000117.php For more Lupine Publishers Open Access Journals Please visit our website:http://www.lupinepublishers.com/ For more Journal of Hepatology Research articles Please Click Here: https://lupinepublishers.com/gastroenterology-hepatology-j...

Advanced Hepatocellular Carcinoma in A ScottishPopulation – Current Experience and the Future by Baxter MA in Current Trends in Gastroenterologyand Hepatology in Lupine Publishers Sorafenib is the current first line standard of care in patients with advanced hepatocellular carcinoma (HCC). Several other drugs are emerging as efficacious agents in this setting. This article will outline our current real-world experience with sorafenib in a Scottish population as well as discuss the evidence behind new potential therapies in Lupine Publishers. For more information, please go through the below links https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/advanced-hepatocellular-carcinoma-in-a-scottish-population-current-experience-and-the-future.ID.000112.php https://lupinepublishers.com/gastroenterology-hepatology-journal/pdf/CTGH.MS.ID.000112.pdf https://lupinepublishers.com/gastroenterology-hepatology-journal/abstracts/advanced-hepatocellular-carcinoma-...

Reflections About the Gut, A Microbiologist’s Perspective by Bernard AM Van der Zeijst in Current Trends in Gastroenterology and Hepatology in Lupine Publishers Without doubt, the original function of the human gut was to digest and absorb food. Its epithelial cells absorb food after it has been processed to smaller components by enzymatic digestion. Comparable epithelial processes are also found in animals, including sea animals, and plants [1]. Disturbance of the gut homeostasis by infections leads to disease. From mild diarrhea of short duration (e.g. caused by poliovirus, rotavirus, norovirus and Campylobacter) to lethal infections by toxin producing bacteria such as cholera. Cholera often occurs as a result of crowding and poor hygiene. It was very problematic during the first industrial revolution in the UK where poor migrants lived under dismal conditions. h...