Lupine Publishers Current Trends in Gastroenterology and Hepatology

  Abstract Extra pulmonary symptoms may contribute to poor outcome in COVID-19. We compared the frequency of gastrointestinal and sensory manifestations (GSM) between mild and severely ill patients with COVID-19, alone or combined with classic respiratory manifestations (CRM). Hospitalized patients with COVID-19 (n = 357) were classified according to their disease severity by using a neutrophile/lymphocyte ratio value ≥18 for severe illness. Presence of CRM and baseline clinical data were recorded. Presence of >3 liquid evacuations per day (diarrhea), decreased usual bowel movements (constipation), nausea/vomiting, lack of appetite (anorexia), abdominal pain, loss of taste (dysgeusia) and/or loss of smell (anosmia) were personally recorded by the investigators at the study admission. Severely ill patients (47.3%) presented worse clinical markers than mildly ill patients, including higher risk of malnutrition and higher need for non-invasive respiratory support ...

  Abstract The identification of the calcium ration by self-questionnaires validated in the region of Blida and the Wilayas of approximately is one of the rare studies in Algeria. She was interested in a part of the Algerian population with characteristics that do not seem very different from the general population; however, this dietary survey must be supplemented by a study on a representative sample of the general population. The study showed insufficient calcium intake mainly secondary to low consumption of milk and dairy products. This low calcium intake was objectified by the two questioning methods (Fardellone and CERIN), however, it will be desirable to establish Algerian self-questionnaires validated and verified by our learned society. The results obtained are worrying, which obliges us to immediately introduce a prevention and control strategy against the multiple pathologies linked to this low calcium intake, the main one being osteoporosis with its seri...

  Introduction Aristolochic acid (AAs) is a group of nitrophenanthrene compounds comprised of AAI, AAII, AAIII and AAIV, which are widely found in Aristolochia plants and used in herbal therapy and traditional Chinese medicine [1]. Consistent use of aristolochic acids- containing drugs could lead to aristolochic acid nephropathy and subsequent urinary tract tumors [2-4]. Active metabolites of AAs form adducts with DNA, inducing characteristic A-T transversion (A:T to T:A mutation) known as AA mutational signature [5]. In 2017, a study has analyzed AA mutational signature of several datasets and concluded that AAs and their derivatives were widely implicated in liver cancers in Taiwan and throughout Asia [6]. Ever since the paper published, there has been an intensive debate on whether the prevalence of AA signature mutation is high in HCC patients and if this mutation spectra is really correlate with traditional Chinese medicine consumption in Asia. Since no case report...

  Abstract Aim : To determine the aetiologies of acute upper gastrointestinal bleeding (UGIB) in a setting highly endemic for hepatitis B and to describe actual clinical practices in a resource-limited setting. Patients and methods: This study was conducted in two parts. The first part was retrospective from January 1st 2010, to December 31st 2019 on the epidemiological profile of UGIB and the second was a prospective study from December 1st 2017 to May 31st 2018 to evaluate, in a blinded experiment, the actual clinical practices in front of an acute UGIB at the emergency units in Yaounde (Cameroon), and included: recognizing UGIB, assessing for severity, taking emergency measures and prescribing emergency Eosogastroduodenal endoscopy (EGDE). Results : During the retrospective period, 506 patients (prevalence of acute UGIB in the services 5.6%) were included of which 71.3% were men (sex ratio 2.5). The mean age was 49.9 +/- 8 years. Haematemesis was inaugural in 35...

Lupine Publishers |Current Trends in Gastroenterology and Hepatology Abstract Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and is one of the major causes of cancerrelated deaths. HCC is reported to be the second most fatal malignancy. The major risk factors for HCC are well known; the known risk factors include hepatitis C virus (HCV) and hepatitis B virus (HBV). Major advances have been reported in the treatment of HCC. Success of early diagnosis increases when these risk factors are identified, and the cases are followed up. It is reported that in the treatment of early-diagnosed HCC cases, ethanol injection or radiofrequency ablation methods as well as surgical resection should be preferred, particularly in cases without liver cirrhosis and in cases where the tumor is restricted. Similarly, liver transplantation may be an option for patients that meet specific criteria. Keywords: Hepatocellular Carcinoma; Liver Carcinoma; ...

Reproductive Health and Fertility in Transition Clinic for Liver Transplant Patients by Uyen in Current Trends in Gastroenterology and Hepatology in Lupine Publishers. The transition of an adolescent into adulthood is fraught with complexity under the best of circumstances. Misinformation or a lack of medical knowledge during this critical time can place young adults in a position to develop risky behaviors. However, simple well-timed educational interventions can foster healthy, informed decisions which can last a lifetime. Adolescents who have undergone pediatric liver transplantation are a subgroup of teenagers at a particularly elevated risk, in part due to their immunosuppression and comorbid conditions, during this time of developing personal autonomy. As these patients begin to develop and establish their personal and reproductive identities, they may also have limited understanding of the long-term consequences of their decisions about reproductive health, contr...

Primary Liver Cancer in Adults by Mirta D Ambra in Current Trends in Gastroenterologyand Hepatology in Lupine publishers Liver cancer includes two main types: hepatocellular carcinoma (HCC) and intrahepatic bile duct cancer. Incidence and mortality. Calculation of the number of new cases and deaths due to liver and intrahepatic bile duct cancer in the United States in 2018: I. New cases: 42 220. II. Deaths: 30 200. HCC is relatively rare in the United States, although its incidence is increasing, especially in regard to the spread of infection with the hepatitis C virus (HCV). HCC is the most common solid tumor in the world and the third leading cause of cancer-related deaths. https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/primary-liver-cancer-in-adults.ID.000122.php   https://lupinepublishers.com/gastroenterology-hepatology-journal/pdf/CTGH.MS.ID.000122.pdf   https://lupinepublishers.com/gastroenterology-hepatology-journal...

Advanced Hepatocellular Carcinoma in A ScottishPopulation – Current Experience and the Future by Baxter MA in Current Trends in Gastroenterologyand Hepatology in Lupine Publishers Sorafenib is the current first line standard of care in patients with advanced hepatocellular carcinoma (HCC). Several other drugs are emerging as efficacious agents in this setting. This article will outline our current real-world experience with sorafenib in a Scottish population as well as discuss the evidence behind new potential therapies in Lupine Publishers. For more information, please go through the below links https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/advanced-hepatocellular-carcinoma-in-a-scottish-population-current-experience-and-the-future.ID.000112.php https://lupinepublishers.com/gastroenterology-hepatology-journal/pdf/CTGH.MS.ID.000112.pdf https://lupinepublishers.com/gastroenterology-hepatology-journal/abstracts/advanced-hepatocellular-carcinoma-...

Reflections About the Gut, A Microbiologist’s Perspective by Bernard AM Van der Zeijst in Current Trends in Gastroenterology and Hepatology in Lupine Publishers Without doubt, the original function of the human gut was to digest and absorb food. Its epithelial cells absorb food after it has been processed to smaller components by enzymatic digestion. Comparable epithelial processes are also found in animals, including sea animals, and plants [1]. Disturbance of the gut homeostasis by infections leads to disease. From mild diarrhea of short duration (e.g. caused by poliovirus, rotavirus, norovirus and Campylobacter) to lethal infections by toxin producing bacteria such as cholera. Cholera often occurs as a result of crowding and poor hygiene. It was very problematic during the first industrial revolution in the UK where poor migrants lived under dismal conditions. h...

Bariatric Surgery and Pregnancy by Mohamed Nabih EL Gharib in Current Trends in Gastroenterology and Hepatology in Lupine Publishers Obesity represents a dangerous public health concern all over the universe. The World Health Organization suggests that, by 2015, approximately 2.3 billion adults will be overweight and more than 700 million will be obese [1]. https://lupinepublishers.com/gastroenterology-hepatology-journal/fulltext/bariatric-surgery-and-pregnancy.ID.000108.php   https://lupinepublishers.com/gastroenterology-hepatology-journal/pdf/CTGH.MS.ID.000108.pdf https://lupinepublishers.com/gastroenterology-hepatology-journal/abstracts/bariatric-surgery-and-pregnancy.ID.000108.php For more Lupine Publishers Open Access Journals Please visit our website: http://www.lupinepublishers.com/ For more journal of clinical gastroenterology articles Please Click Here: https://lupinepublishers.com/gastroenterology-hepatology-journal/index.php...